منابع مشابه
Are companion diagnostics useful?
We define a companion diagnostics (CDx) test as any diagnostic tool that guides the selection of patient treatment. In the US, these tests include diagnostics cleared by the Food and Drug Administration (FDA), as well as laboratory-developed tests (LDTs) run in CLIA-accredited laboratories. The answer to the title’s question is obviously in the affirmative. We discuss the growing need to improv...
متن کاملPersonalized Medicine in Oncology and Companion Diagnostics: Development and Challenges
The core of the whole concept of personalized medicine is to tailor medical practice, from prevention, diagnosis, treatment to prognosis, based on the underlying pathophysiological changes of the disease and the patient. More specifically, this approach may include new diagnostic tools to determine genetic alterations and expression, including the noncoding genetic elements, in order to more pr...
متن کاملCompanion diagnostics: changing patient management
At the European Multidisciplinary Cancer Congress (EMCC), held in Stockholm in September 2011, a recurring theme in many of the workshops was personalised medicine, including the latest developments in prognostic and predictive biomarkers. Such markers, it is hoped, will enable clinicians to use available resources to best effects-by offering treatments to only those patients most likely to ben...
متن کاملChallenges in the codevelopment of companion diagnostics
The goal of personalized medicine, to effectively customize diagnosis, treatment and prevention of disease to one’s genetic composition, is one that has been known and sought for many years. Increasingly, molecular companion diagnostics based on one’s inherited or somatic biomarkers are desired to ensure the effective, safe develop ment and application of a personalized drug. This has been ref...
متن کاملThe Retrospective Approach To Companion Diagnostics
Companion diagnostic tests, developed for use in conjunction with therapeutic drugs and biologics, drive personalized medicine. These tests, which are regulated by the U.S. Food and Drug Administration as medical devices when they are marketed as kits,[1] are indispensable to personalized medicine because they provide “information that is essential for the safe and effective use of a correspond...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Seminars in Nuclear Medicine
سال: 2016
ISSN: 0001-2998
DOI: 10.1053/j.semnuclmed.2015.09.002